Research Internship Chemical Biology

What it is about

You work on an individual laboratory project in Chemical Biology that involves the development and evaluation of novel small molecules and their target proteins using affinity-enrichment (pulldowns) and quantitative mass spectrometry. In the end you will master fundamental methods of chemical proteomics, be able to critically evaluate mass spectrometry data, and possess either cell culture or synthesis skills.

What you will be able to do

• Fundamental experimental skills of chemical proteomics
• Understanding of possibilities and limitations of affinity-based proteome profiling
• Critical analysis of mass spectrometry readouts
• Acquisition of cell culture knowledge or competencies in chemical synthesis
• Preparation and presentation of scientific reports and talks

What the module consists of

• LaborpraktikumConducting the individual research project including pulldowns, mass spectrometry and either synthesis or cell culture
• Seminare / PräsentationenRegular participation in weekly group seminars for presenting and contextualizing the results

Teaching method

• Learning by doingMain method: hands-on execution of the project under supervision to directly impart experimental skills
• Individuelle Demonstration und ProtokolleExplanation and demonstration of the methods as well as written protocols, initially under close supervision, then independently
• One-to-one DiskussionenOngoing review of protocol variants and results for project management
• Präsentationen und ReportwritingTraining of presentation and written reporting skills through seminar talks and final report