Analysis of Epigenomic Data

What it is about

You will learn how to analyze epigenomic NGS data (e.g., ChIP-seq, WGBS) and integrate it with gene expression data. At the end you will be able to download, preprocess, analyze (alignment, quality control, peak/methylation analysis) and biologically interpret the results.

What you will be able to do

• Use Linux and R
• Distinguish between ChIP-seq and WGBS
• Understand the structure of sequence files
• Manipulate and preprocess sequence files
• Apply software for ChIP-seq and WGBS analyses
• Interpret analysis results
• Query results for specific biological questions

What the module consists of

• PraktikumCentral teaching method: Practice-oriented work on current research questions in plant epigenetics under supervision
• ComputerübungenCarrying out the NGS analysis steps (Linux, R, alignment, peak/methylation analysis)
• LiteraturstudiumDevelopment of the background and placement of the analysis results
• PräsentationPreparation and presentation of the results to the group

Teaching method

• Computer practicalPractical application and training of data analysis skills
• Individualisierte AnleitungClose supervision to clarify individual questions and methods
• Kritische Diskussion mit Betreuern und ForschungsgruppenmitgliedernInterpretation and contextualization of analysis results in the scientific context