What it is about
You will learn methods of proteomics and how they are applied in basic research, medical research, and drug development. After the module you will be able to plan proteomic experiments, analyze mass spectrometry data, and evaluate the results in an experimental context.
What you will be able to do
- Methodical fundamentals of proteomics (sample preparation, fractionation, MS, identification, quantification)
- Theory and applications of common methods
- Independent work with chromatographic and mass spectrometric methods
- Developing answers to biological/medical questions (e.g. PTMs, biomarkers, protein interactions)
- Conceptualization of quantitative and qualitative proteomics experiments and assessment of the results
- Application and critical evaluation of proteomic software tools
- Interpretation of mass spectrometric peptide spectra and use for protein identification/quantification
- Structured presentation and explanation of scientific questions
What the module consists of
- VorlesungDelivery of theoretical foundations, methods and application examples
- Übung/PraktikumPractical data analysis, application of software tools and case study work
Teaching method
- VorlesungIntroduction to the proteomic methods toolkit and development of solutions to questions
- Praktikum/ÜbungIndependent data analyses with provided software tools; intensive interaction with instructors