Research Project: in silico Evolutionary Genetics of Plants and Pathogens

What it is about

In this module you work on a research project in evolutionary genetics of plants and pathogens. You analyze either genomic Next-Generation-Sequencing (data) or model biological questions with stochastic simulations in R and learn to evaluate the results statistically and discuss them critically.

What you will be able to do

• Use of classical bioinformatics tools for NGS data
• Secure use of the Linux operating system and a computing cluster
• Fundamental statistics and data analysis with R
• Recognizing and processing the steps from raw data to SNP calls
• Carrying out a de-novo genome assembly of simple genomes
• Formulation and implementation of stochastic models in R
• Critical evaluation of analysis pipelines and sources of error
• Writing a scientific project report

What the module consists of

• Praktisches ForschungsprojektImplementation and deepening of a project either on NGS/genomic data or on a mathematical model
• ComputerübungenApplying software tools and programming for analysis or simulation
• Selbstständige LiteraturarbeitSelection and summarization of relevant literature to address the research question

Teaching method

• ComputerübungTo convey practical analysis and programming skills
• Praktisches ForschungsprojektTo train independent work on a concrete question
• Autonomes ArbeitenFor literature research, question development and report writing