Methoden der Genomanalyse

What it is about

You learn how genomes are structured and which methods are used to analyze DNA and RNA sequences. In the end you will be able to explain concepts such as genes, regulatory sequences, alternative splicing, microRNAs, repeats, pseudogenes as well as orthology/paralogy and practically apply basic genome analysis methods.

What you will be able to do

• Understand and reproduce important concepts of genome analysis
• Conduct gene prediction
• Apply prediction of microRNA binding sites
• Identify DNA sequence motifs
• Predict RNA structures
• Relevant terms: operons, alternative splicing, SNPs, pseudogenes, repeats, orthology/paralogy

What the module consists of

• VorlesungConveying fundamental concepts, methodological approaches and typical problems of genome analysis
• ÜbungDeepening of lecture content, discussion of scientific publications, demonstration and application of methods on case studies

Teaching method

• Vortragto introduce fundamentals and methods
• Diskussion/Präsentation von Papers in der Übungexplain current research findings and practice applying bioinformatic analyses