What it is about
You learn how to formulate, mathematically describe and solve kinetic models of cellular and biochemical reactions – from classical approximations to numerical and stochastic methods. In the end you can practically implement these models (e.g., in Mathematica), distinguish between ensemble- and single-molecule considerations, and analyze typical single-molecule phenomena such as processivity or randomness.
What you will be able to do
- Understand and apply fundamental kinetic models
- Implement kinetic schemes into quantitative models (e.g., in Mathematica)
- Distinguish global kinetic models from partial-step models
- Understand differences between ensemble- and single-molecule measurements
What the module consists of
- VorlesungIntroduction to reaction schemes, differential equations, classical approximations as well as numerical and stochastic solution approaches
- ÜbungImplementation of the theoretical background on concrete biological and biochemical models; working on exercise problems; seminar talks and discussion of original literature
Teaching method
- Vorlesung mit SkriptConveying the theoretical foundations and solution approaches
- Übungen mit BeispielprogrammenPractical implementation of models and training of the exam-relevant competencies
- Seminarvorträge / LiteraturbearbeitungDemonstrating relevance using original literature